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When doctors scheduled a brain MRI for Angela Polizzotti鈥檚 10-month-old son, she was understandably concerned about the procedure. She couldn鈥檛 imagine a baby like Blake lying still through the exam, which could take up to an hour. But she didn鈥檛 like the idea of anesthetizing her child to keep him motionless. 鈥淗e was so little, and he鈥檇 never had anesthesia before,鈥� Polizzotti says. 鈥淚 was nervous about sedating him.鈥�

Luckily, Boston Children鈥檚 Hospital鈥檚 radiology department had been developing a program called Try Without Anesthesia to reduce the number of children who are sedated for their imaging exams. The team knew that limiting the use of anesthesia would have a twofold benefit: Patients could get their imaging sooner and avoid the potential risks associated with anesthesia.¹ When the Polizzotti family found out about the program, they decided to try the exam without sedating Blake.

When doctors at Boston Children鈥檚 Hospital scheduled a brain MRI for 10-month-old Blake Polizzotti, his mother was nervous about sedating him. She agreed to Try Without Anesthesia to explore options outside of sedation.

鈥淥bviously, MRI scans are not painful procedures. The only reason children need sedation is because they struggle to remain motionless long enough to capture clear images,鈥� says Richard L. Robertson, MD, radiologist-in-chief and chair of the department of radiology at Boston Children鈥檚 Hospital. 鈥淏y avoiding sedation, you reduce the overall risk, time, and cost of doing a diagnostic study.鈥�

Since radiologists at Boston Children鈥檚 Hospital began exploring alternatives to anesthesia around 2007, they have formalized the Try Without Anesthesia program to get children through imaging exams without sedation. By helping children like Blake lie still during MRI procedures, the program has reduced sedation rates from 55% to 15% for these procedures. 鈥淭his program provides a valuable service for patients and their families while also making our radiology practice safer and more efficient,鈥� says Robertson, who is also the John A. Kirkpatrick associate professor of radiology at Harvard Medical School.

Getting Started

Prior to 2007, radiologists at Boston Children鈥檚 Hospital generally assumed that most children younger than 7 required sedation to remain still during MRI procedures. But as the hospital鈥檚 appointment volume increased and the wait times for sedation swelled beyond 60 days, that assumption left many patients and their families waiting months for answers. To get children through imaging faster, the radiology team began exploring ways to reduce the need for sedation for imaging.

Around that time, Robertson learned about MRI-compatible video goggles that allowed children to watch movies during scans 鈥� a distraction that reduced the need for sedation by nearly 20% in early studies.² Impressed with the results, Robertson asked hospital administrators to invest in the goggles, and they quickly agreed. 鈥淭he administration understood the importance of reducing the use of anesthesia,鈥� Robertson says. 鈥淭hey recognized that when you avoid sedation, you decrease the risk of the exam for the patient. It鈥檚 also significantly less expensive.鈥�

According to a study published in the Radiology, the average cost of an outpatient MRI in 2011 was $665 without anesthesia and $902 with anesthesia.³ Other research suggests that pediatric MRI costs for sedated and anesthetized patients are, respectively, 3.24 and 9.56 times higher than MRI costs for patients who stay awake.⁴

By monitoring the exams from the reading room through the picture archiving and communication system (PACS), Robertson and his fellow radiologists could instantly determine whether the goggles and other techniques were working for each child. 鈥淥ur radiologists actively supervise MRI cases as they鈥檙e being performed,鈥� Robertson says. 鈥淲e set up our PACS with the ability to send images at the end of each series acquisition, so we can watch the study in action and instantly decide, 鈥榃e鈥檝e captured the information we need; we can stop the exam now,鈥� or, 鈥楾his child鈥檚 moving; we need to repeat that scan to get a clear picture.鈥欌��

Scanning Faster

After seeing early success with 5- to 7-year-old children, who seemed most engrossed in the movies, the radiology department began expanding the department鈥檚 efforts to reduce MRI anesthesia in other age groups. 鈥淲e decided that the children who are particularly vulnerable due to their small size and for whom we wanted to minimize sedation the most were babies up to age 1,鈥� Robertson says. 鈥淪o, in 2010, we started focusing on reducing sedation in that population.鈥�

Richard L. Robertson, MD, radiologist-in-chief and chair of the department of radiology at Boston Children鈥檚 Hospital, co-created the Try Without Anesthesia program to reduce the radiology department鈥檚 reliance on anesthesia for imaging procedures.

As part of this work, the radiology department adjusted the imaging protocols for faster acquisitions so that babies would be in the scanner for less time. 鈥淪hortening the image acquisition times is the single most important thing that we can do as radiologists to reduce the need for anesthesia,鈥� Robertson says. 鈥淲e found that many children can stay still for one minute but not for four minutes during a standard acquisition.鈥�

To convince radiologists that faster protocols were diagnostically equivalent to standard acquisitions, Robertson and his colleagues conducted a blind review of brain MR imaging comparing fast scans to standard scans. After collecting images from 60 cases and redacting the image acquisition details, Robertson asked radiologists in his department to compare each image set. 鈥淗alf of the time, they said the conventional acquisition was better, and the other half of the time, they said the faster acquisition was better,鈥� says Robertson, who outlined his findings in a study that was published last year.⁵ 鈥淭hrough the blind review, the radiologists saw that faster acquisitions were diagnostically equivalent, which secured their buy-in.鈥�

Although it wasn鈥檛 a formal program yet, more nurses, technologists, and radiologists were convinced of the idea of trying exams without sedation. They allowed extra time for parents to swaddle and calm their babies before their exams and utilized faster acquisition times to shorten the length of each scan. Through these informal efforts, the radiology department reduced the sedation rate for babies under age 1 by more than half 鈥� cutting the use of anesthesia from about 55% to 20% in that population within a couple of years.

Formalizing the Program

With positive results from their early efforts, the radiology department began to formalize and expand the Try Without Anesthesia program. In 2015, Robertson convened a group of schedulers, technologists, radiologists, nurses, MRI physicists, image analysts, and faculty members from radiology鈥檚 research center to develop the program logistics. He also engaged the hospital鈥檚 information strategy department and external MRI vendor to establish the program鈥檚 technology workflow for faster imaging protocols and streamlined appointment-setting prompts.

鈥淔or this initiative to work, we needed to look at all of the factors around imaging,鈥� Robertson says. 鈥淭he schedulers had to be able to identify candidates upfront. The radiologists needed to know what imaging protocols to use to minimize exam durations, and the techs and nurses had to be patient in working with the children. The physicists and image analysts also had a significant role in redesigning the imaging protocols, and the informatics team helped sup-port the workflow.鈥�

Through monthly meetings, the committee developed the workflow for the Try Without Anesthesia program 鈥� starting with a digital dashboard that was developed in-house to aggregate information from the electronic medical record, scheduling system, PACS, and protocoling applications to help identify candidates for the program. Schedulers are prompted to share the benefits of the program whenever families call to schedule anesthesia appointments, and the radiologists and technologists can also flag patients who seem like good candidates for the program based on certain indications or conditions.

The committee officially launched the Try Without Anesthesia program in January of 2016. The team initially limited the sedation-free appointments to four 105-minute slots every Sunday afternoon, when the hospital鈥檚 slower schedule permitted 30 minutes of one-on-one prep time with a child life specialist and 75 minutes of scanning time. These appointments initially focused on patients between 4 and 7, since patients in that age group had success using the video goggles to avoid sedation in prior years.

As more families learned about the anesthesia-free option, however, the program quickly expanded. By the time the Sunday-focused program concluded in July of 2019, 320 patients between the ages of 1 and 16 had participated in the Sunday Try Without Anesthesia appointments alone, with 91% of patients successfully completing the exams without anesthesia.

Recruiting Patients

The program received an additional incentive in December of 2016, when the Food and Drug Administration (FDA) issued an about the potential neurocognitive effects of prolonged anesthesia exposure in young children. The warning urged pediatric healthcare professionals to balance the risks and benefits of sedation. 鈥淭he FDA advisory strengthened our resolve to advance the program,鈥� Robertson says. 鈥淏ut we needed a more structured approach if we were going to expand it further.鈥�

As the Try Without Anesthesia program coordinator, Kellyn Mahan helps families prepare for pediatric imaging by exploring alternatives to sedation.

To that end, Robertson hired Kellyn Mahan, who worked as a scheduling coordinator in the radiology department for several years and who had recently finished training to become a child life specialist, to take ownership of Try Without Anesthesia as the program coordinator in January of 2017.

Mahan鈥檚 main responsibility was to recruit patients for the program by calling families to discuss their options without sedation and informing families about the program when they called to schedule anesthesia appointments. Nurses and technologists also recommended the program when children seemed calm, unfazed, or even eager to interact with them in the prep room before an anesthesia appointment.

To reach more patients, Mahan created brochures to distribute throughout the radiology waiting rooms and local clinics and collaborated with the marketing department to develop materials to educate referring providers about the pro-gram. 鈥淲e want to reach as many patients as possible,鈥� Mahan says, 鈥渟o anything we can do to spread the word about these appointments is beneficial.鈥�

Additionally, to keep the program top-of-mind among referring providers, Robertson and other departmental leaders talked about the importance of reducing anesthesia rates in weekly operations meetings, multidisciplinary conferences, and the radiology group鈥檚 annual quality management plan. 鈥淲e constantly bring up the Try Without Anesthesia option,鈥� he says. 鈥淣ow, a lot of referring clinicians specifically request this approach for their patients, which has been really nice to see.鈥�

Imaging at Bedtime

As the program grew in popularity, Mahan worked with the committee to explore other alternatives to anesthesia. Recognizing that children were likely to remain still for an MRI if they were asleep, the committee decided to try later appointment times to coincide with patients鈥� bedtimes. In October of 2017, the Try Without Anesthesia program began offering 9 p.m. appointments one day week. These appointments allow families to schedule exams when the hospital is quiet and their children are sleepy. Since the hospital already had MRI technologists and radiologists working over-night shifts, staffing wasn鈥檛 a big issue.

鈥淥ur intention was to bring in children when they鈥檙e as tired as possible,鈥� says Mahan, who initially advised patients鈥� families to keep children from napping on the day of the scan 鈥� but that approach just made kids cranky, not sleepy. 鈥淲e realized that our success depended not just on how tired the kids were but on how well we helped families prepare for these appointments.鈥�

Now, as soon as a family schedules a Try Without Anesthesia appointment, Mahan sends them a detailed email that explains the imaging process and encourages families to help children practice for their exam. The email includes a link to a video that plays the sounds of an MRI machine, and Mahan sends the earmuffs and noise-reducing ear putty that children can wear during their scan. 鈥淲e suggest that they play the sounds as much as possible during the child鈥檚 bedtime so that the child gets used to hearing the noises,鈥� Mahan explains. 鈥淲e also ask them to use the ear protection leading up to the appointment because it鈥檚 often a new sensation for the children.鈥�

Polizzotti played the MRI sounds for her son Blake during naps and bedtimes leading up to his appointment. 鈥淚t definitely helped,鈥� she says. 鈥淏y the time he went in for his exam, the noise didn鈥檛 startle him at all.鈥�

Replicating Routines

For additional support, Mahan asks a lot of questions about each child鈥檚 bedtime routine so that she can recreate that environment when families arrive for their nighttime appointments. She encourages families to bring their children鈥檚 blankets or stuffed animals to help them relax and asks families to arrive for their nighttime appointments around 7:15 p.m., giving the children plenty of time to get comfortable and fall asleep before their 9 p.m. exams, which the department now offers two days a week and hopes to eventually offer five days a week.

By offering late-night appointment times, MRI-compatible video goggles, child-friendly exam room d茅cor, and plenty of patience, technologists and radiologists at Boston Children鈥檚 Hospital help young patients get through imaging exams without anesthesia.

鈥淭hey gave Blake a stuffed animal and provided a rocking chair for me to rock him to sleep and even allowed his favorite blanket to go in with him,鈥� Polizzotti says. 鈥淢y son is obsessed with Michael Bubl茅, so they actually played Michael Bubl茅 music in the background, which really helped soothe him. They gave him little headphones, and he slept through the whole thing.鈥�

Over time, the hospital added more MRI-compatible tools to keep kids comfortable inside the scanner, including a crib made of PVC pipes. They also began offering custom DockATots, oval-shaped pillows that cradle babies and prevent them from rolling around. 鈥淭he DockATot company donated products to us,鈥� Mahan says. 鈥淭hey even changed the metal zipper to a plastic zipper so that we can use them to transfer sleeping children onto the MRI bed.鈥�

If all else fails, radiologists allow parents to join their children on the MRI bed during a scan. 鈥淎lthough it鈥檚 not optimal, it can be one of our last resorts to keep a child still,鈥� Robertson says.

When Blake Polizzotti returned for a spinal MRI about six months after his first exam, he tossed and turned until his mother joined him on the bed. 鈥淚 had to do a half-plank over his legs for the duration of the 30-minute exam, but he fell asleep as soon as I got on the bed,鈥� Polizzotti says. 鈥淏ecause the team was so patient and willing to try anything, my son made it through both MRIs without sedation.鈥�

Reporting Results

Blake is just one of many sedation-free success stories at Boston Children鈥檚 Hospital. Robertson estimates that prior to 2007, about 55% of the hospital鈥檚 patients were sedated for MRI exams, but now thanks to the Try Without Anesthesia program, only about 15% of children require sedation for these studies.⁶ For certain cases 鈥� like a high-resolution study for a pre-operation epilepsy evaluation, for example 鈥� sedation may still be the best option, but many children just need a little patience and preparation to get through an exam without anesthesia.

By working together with families to help children through imaging procedures without sedation, the radiology department is creating a more collaborative approach to care. 鈥淭hrough the Try Without Anesthesia program, families become more involved in the MRI scan,鈥� Mahan says. 鈥淓ven if patients must ultimately be sedated, families appreci-ate having the opportunity to at least try it first without anesthesia.鈥�

For the Polizzotti family, the program positively impacted their overall healthcare experience. 鈥淚t gave us a lot of peace of mind and relief,鈥� Polizzotti says. 鈥淢y husband and I were thrilled that Blake didn鈥檛 have to go through the sedation process. We鈥檙e so thankful to the amazing team that runs this awesome program. You can tell that they want your baby to get through this as much as you do.鈥�

As the program moves forward, the team continues to explore new tools and creative techniques to prepare children for imaging. They鈥檙e currently looking into augmented reality and even a therapy dog to keep kids at ease. It鈥檚 all part of the group鈥檚 ongoing commitment to minimize the use of anesthesia. 鈥淎s much as possible, we ought to avoid sedation of children for diagnostic imaging procedures,鈥� Robertson says, 鈥渂ut there鈥檚 not one right way to go about this. It requires some experimentation and a real dedication to doing this because it鈥檚 the right thing to do. You provide a valuable service to the patient, and in the end, it can actually be more efficient for your practice, as well.鈥�